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Gene regulation, not just genes, is what sets humans apart from primates

bioinformatics | biology | biotechnology | dna | gene regulation | genes | genome | science | technology

The striking differences between humans and chimps aren’t so much in the genes we have, which are 99 percent the same, but in the way those genes are used, according to new research from a Duke University team.

Bioengineers Devise ‘Dimmer Swith’ To Regulate Gene Expression In Mammal Cells

bioengineering | biohacking | biotechnology | dna | gene regulation | genetic engineering | genetics | rna | rnai | synthetic biology | technology

Three Boston University biomedical engineers have created a genetic dimmer switch that can be used to turn on, shut off, or partially activate a gene’s function. Professor James Collins, Professor C

Mechanism of microRNAs deciphered

biotechnology | dna | gene regulation | genes | genome | rna | rnai

Over 30% of our genes are under the control of small molecules called microRNAs. They prevent specific genes from being turned into protein and regulate many crucial processes like cell division and development, but how they do so has remained unclear.

Scientists discover new class of RNA

biology | biotechnology | dna | gene regulation | genome | rna | science

The last few years have been very good to ribonucleic acid (RNA). Decades after DNA took biology by storm, RNA was considered little more than a link in a chain–no doubt a necessary link, but one that, by itself, had little to offer.

Scientists map key landmarks in human genome

biology | biotechnology | dna | gene regulation | genome | science | technology | transcription factors

Dana-Farber Cancer Institute researchers have developed a powerful method for charting the positions of key gene-regulating molecules called nucleosomes throughout the human genome. The mapping tool could help uncover important clues for understanding and diagnosing cancer and other diseases, the scientists say.

Regulating the nuclear architecture of the cell

biology | cancer | cell biology | dna | gene regulation | genome | immune system | rna | rnai

An organelle called the nucleolus resides deep within the cell nucleus and performs one of the cell’s most critical functions: it manufactures ribosomes, the molecular machines that convert the genetic information carried by messenger RNA into proteins that do the work of life.

‘Cancer prognosis gene’ found to control the fate of breast cells

bioengineering | biomedical | biotechnology | cancer | gene regulation | transcription factors

The gene, called GATA-3, is in a family of genes that guides development of stem cells into mature cells. University of California, San Francisco researchers have now found that GATA-3 is also required for mature mammary cells to remain mature in the adult.

Jumping gene could provide non-viral alternative for gene therapy

bioengineering | biohacking | biology | biotechnology | dna | gene regulation | gene therapy | genetic engineering | genome

A jumping gene first identified in a cabbage-eating moth may one day provide a safer, target-specific alternative to viruses for gene therapy, researchers say. They compared the ability of the four be

Genome code cracked for breast and colon cancers

bioinformatics | biotechnology | cancer | cell biology | cell signaling | gene regulation | genes | genome

Scientists have completed the first draft of the genetic code for breast and colon cancers. Their report, published online in the September 7 issue of Science Express, identifies close to 200 mutated

Research Identifies Protein In Mice That Regulates Bone Formation

biotechnology | gene regulation | genes | genetic engineering | transcription factors

Osteoporosis, a disease characterized by a decrease in bone mass and density and which makes people more susceptible to bone fractures and deformities, afflicts some 10 million Americans over the age of 50.

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